Iron deficiency: Spot the symptoms, understand the causes & rebalance

Eisenmangel: Ursachen, Symptome und Behandlung

Tiredness, difficulty concentrating or brittle nails: Symptoms like these are often linked to iron deficiency. As a trace element, iron plays a central role in the body, supporting functions like blood formation and oxygen transport. Find out what triggers a deficiency and when treatment is advisable.

Frequently asked questions about iron deficiency

What does the body need iron for?

Iron is a vital trace element as it performs key functions in the body: It’s particularly important for producing the blood pigment haemoglobin, which ensures oxygen is transported around the body. Iron also supports the immune system and the production of certain neurotransmitters in the brain, along with other nervous system processes. A balanced iron status is therefore a basic prerequisite for energy, concentration and a well-functioning immune system.

Iron deficiency is diagnosed when the body’s iron reserves fall below a certain level. While severity levels can vary, the two best-known forms are:

  • Latent iron deficiency without anaemia: Stores are already reduced, but haemoglobin levels remain normal. Symptoms don’t necessarily occur at this stage.
  • Iron deficiency anaemia: The deficiency is severe enough to cause anaemia as well. Iron deficiency is classed as the most common cause of anaemia.

What are the symptoms of iron deficiency?

How pronounced and how long-standing the deficiency is affects which symptoms appear. Common symptoms include:

  • muscle weakness and reduced endurance
  • irritability and dizziness
  • cognitive issues such as poor concentration, memory problems or reduced learning ability
  • headaches
  • mood swings
  • appetite for clay or soil
  • rough, brittle nails
  • dry skin, cracked mouth corners and a burning tongue sensation
  • hair loss

Because these complaints are non-specific and can occur in other conditions too, it's worth having a blood test if symptoms persist. Only a root cause analysis, including a ferritin test, can reliably show whether iron deficiency is the problem.

Are paleness and fatigue reliable signs of iron deficiency?

Paleness arises because less haemoglobin is produced in iron deficiency, and haemoglobin is what gives skin its colour. On its own, though, paleness isn’t a reliable sign of iron deficiency, as it can also be caused by factors such as cold, circulatory problems or an individual’s natural skin tone.

Fatigue in iron deficiency occurs because less oxygen is being transported around the body. However, fatigue often has other causes – for example depression, kidney disease, thyroid dysfunction or chronic hepatitis. It's therefore important to have the root cause analysed by a medical professional before starting iron therapy.

 Lena – patient with iron deficiency
Before, I was completely exhausted and went through really depressive phases – but I thought it was because I was juggling two small children with work and studies.
Lena Patient with iron deficiency

What causes iron deficiency?

The most common causes of iron deficiency are increased iron requirements, recurrent blood loss (for example through menstruation), and inadequate iron intake due to an unbalanced diet. Requirements are higher, for instance, during growth phases and in pregnancy, when the body needs more iron to produce blood. Intensive sport also raises demand, as more iron is lost through sweat and micro-injuries. Other possible causes include:

  • chronic inflammatory bowel diseases
  • chronic illnesses that affect iron availability
  • reduced iron consumption in coeliac disease

Daily iron requirement

The body can’t produce iron itself and relies on dietary intake. Iron requirements differ markedly according to gender and life stage:

  • Men (18–65 years): 11 mg per day
  • Men (66 and older): 8-10 mg per day
  • Women (18–65 years): 16 mg per day – the higher requirement is due to regular blood loss during menstruation
  • Women (66 and older): 8–10 mg per day – after menopause, requirements fall because menstruation stops
  • Pregnant women: 30 mg per day
  • Breastfeeding women: 20 mg per day

Important: Because it’s scarcely possible to meet the increased iron requirement in pregnancy through diet alone, iron supplements are often prescribed for women during pregnancy or while breastfeeding.

Dr. Thomas Rosemann
A balance is needed between intake and loss – and there are simply some people who lose more. Menstruating women are one example.
Dr Rosemann Chair of Primary Care, University of Zurich and Head of the Institute for Primary Care, University Hospital Zurich

Other risk groups

Besides taking gender, age and pregnancy into account, there are also other groups of people with higher iron requirements or a greater risk of deficiency:

  • Children and adolescents going through rapid growth, because the body needs more iron for blood formation during this phase.
  • People who do intensive competitive sport, as more iron is lost through sweat, micro-injuries and an increased metabolic rate.
  • People who follow a vegetarian or vegan diet, because plant-based iron is absorbed less efficiently than iron from animal sources.
  • People who donate blood regularly, since each donation also removes iron that the body then has to replenish.

If you belong to one of these groups, it’s worth keeping a close eye on your iron level and having it checked by a doctor if needed.

Testing iron deficiency

To reliably determine the body’s iron levels, a blood test is carried out to check ferritin levels. This protein indicates how full the iron stores are. While there are no standard threshold values, a general guideline is: If ferritin is below 50 nanograms per millilitre of blood (ng/ml), symptoms can already occur; below 15 ng/ml, iron levels are too low. It’s not possible to state a single ferritin value that’s considered dangerous for everyone – but as a general principle, the lower the value, the more pronounced the deficiency tends to be.

For a reliable diagnosis, CRP should also be measured. This protein indicates acute inflammation and infections, which can artificially raise ferritin and distort the test result.

How reliable are self-tests from the pharmacy?

With just a small prick in the fingertip and a result within minutes, it’s no wonder iron self-tests from pharmacies remain popular. Most of these tests measure the person’s ferritin level, which gives an indication of the body’s iron stores. However, such tests are only reliable when the deficiency is severe. Inflammatory conditions can also skew the results, as ferritin levels may rise regardless of the actual iron status.

Self-tests therefore provide only a first indication and don’t replace a thorough diagnosis by a healthcare professional. If you’re experiencing recurring symptoms or are unsure, it’s best to discuss the next step with a doctor and have your iron status checked with a blood test.

How is iron deficiency treated?

As a rule, not every case of iron deficiency needs treatment. Treatment is primarily recommended when anaemia has been diagnosed – that is, when the haemoglobin concentration is too low. It’s important to note that low iron levels don’t necessarily cause symptoms.In the case of iron deficiency without anaemia, treatment makes sense mainly when symptoms occur. Options typically include tablets or infusions.

People with a deficiency should never take iron supplements on their own initiative, but only under medical supervision and for a limited period.

Iron tablets

Iron tablets are usually better tolerated by the body, because the iron is supplied in several small doses over a longer period rather than the stores being completely re-filled in one or two sessions.

Iron infusions

Iron infusions are generally a second option and are only considered if tablets cause gastrointestinal side effects or don’t produce the required ferritin rise. An iron infusion should always be medically supervised. In very rare cases, allergic reactions can occur.

Iron overdose: Is this possible?

Overdose through food alone is very unlikely. However, if iron supplements are accidentally taken in larger amounts than prescribed, acute iron poisoning can occur. Symptoms include nausea, vomiting, abdominal pain or diarrhoea and can be dangerous even in adults. In children, an overdose can be life-threatening. Iron tablets should therefore always be stored out of children’s reach. If too much iron is taken over a longer period, chronic iron overload can develop. This is when iron accumulates in organs such as the liver, heart or pancreas, potentially causing long-term damage.

Follow-up after treatment

To check whether treatment has worked, the medical practitioner will take another blood sample. In patients who take tablets, haemoglobin is checked after four weeks, while iron stores (ferritin) are measured no sooner than six to eight weeks. In patients treated with infusions, follow-up takes place at twelve weeks, because ferritin levels rise sharply immediately after treatment.

Prevent iron deficiency with the right diet

If you already have iron deficiency, it’s difficult to correct it with iron-rich foods alone – supplements are generally needed as well. For prevention, however, diet plays an important role, since iron is found in varying amounts in almost all foods.

Facts to note:

  • Iron from animal-based foods is absorbed particularly well; iron from plant-based foods is absorbed somewhat less efficiently. Especially iron-rich foods include red muscle meat and liver, pulses such as lentils or soybeans, nuts and seeds such as sunflower seeds, and vegetables and herbs such as watercress or parsley.
  • Ascorbic acid (vitamin C) improves iron absorption. Having a piece of fresh fruit with a meal is therefore recommended. Fermented foods such as sauerkraut and organic acids from citrus fruits also support iron uptake.
  • Iron can easily be combined with vitamin B12 as a supplement. It’s particularly important to ensure an adequate intake of both nutrients if you follow a vegetarian or vegan diet.

Iron-rich foods at a glance

The amount of iron different foods provide varies considerably. The following overview shows the iron content of selected foods per 100 grams:

  • cocoa powder, unsweetened (49 mg)
  • blood sausage (30.0 mg)
  • liver (average of beef, veal, pork) (11 mg)
  • pumpkin seeds (8.2 mg)
  • sesame seeds (7.7 mg)
  • mussels, cooked (4 mg)
  • oats (3.5 mg)

These figures show: Iron is found in both animal and plant foods. It’s important to remember that the body never absorbs all the iron contained in a food, only a fraction of it. Exactly how much depends on factors such as whether it’s haem iron (from animal sources, around 15–35% absorption) or non-haem iron (from plant sources, around 2–15% absorption).

The body also actively regulates absorption: When iron levels are low, significantly more iron is taken up from food than when stores are full. Daily iron requirements are around 10 to 15 milligrams, depending on age and gender. By regularly eating a varied, balanced diet, most people can meet their daily needs through food, depending on their individual circumstances.

Foods that inhibit iron absorption

Certain substances also affect how much iron the body can actually absorb. Some foods contain compounds that inhibit iron uptake in the gut:

  • Tannins from coffee, tea or wine bind iron and make it harder to absorb.
  • Phytates from wholegrain cereals, pulses and nuts can bind iron in the gut and reduce absorption.
  • Soy proteins, for example from tofu or soy milk, also inhibit iron absorption.
  • Calcium-rich foods such as milk and dairy products can impair iron absorption when consumed at the same time.
  • Eggs contain phosvitin, a protein that further reduces iron absorption.

Important: You don’t need to avoid a single inhibiting food altogether. Timing is what matters – if you avoid consuming coffee, tea or large amounts of dairy when eating iron-rich foods, you can significantly improve iron absorption. As a rule, a varied diet generally compensates well for the inhibiting effects of individual foods. 

What would you like to read now?

Well looked after with CSS

Nutrition counselling

Make long-lasting changes to your eating habits with help from professionals.
To the offer

Health Coach

Get personal advice on health-related matters.
Discover the service

CSS Coin

Shop in your region and pay 30% less.
Find out more